| 中文名 | 吉非替尼 |
| 英文名 | Iressa |
| 别名 | 吉非替尼 易瑞沙(吉非替尼) 湖北吉非替尼原料药 吉非替尼(易瑞沙) 易瑞沙(阿斯利康公司的抗肿瘤新药) N-(3-氯-4-氟苯基)-7-甲氧基-6-(3-吗啉-4-丙氧基)喹唑啉-4-胺 4-[(3-氯-4-氟苯基)氨基]-6-[3-(4-吗啉基)丙氧基]-7-甲氧基喹唑啉 |
| 英文别名 | Iressa IRESSA ZD 1839 GEFITINIB AKOS 91371 Gefitinib base Gefitinib(TINIBS) Gefitinib, Iressa, ZD1839 GEFITINIB RELATED COMPOUND n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]- N-(3-Chlor-4-fluorophenyl)-7-[methoxy-6-[(3-morpholin-4-yl)propoxyl]-quinazolin-4-yl]amine Gefitinib N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine Gefitinib |
| CAS | 184475-35-2 |
| EINECS | 643-034-7 |
| 化学式 | C22H24ClFN4O3 |
| 分子量 | 446.9 |
| InChI | InChI=1/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27) |
| 密度 | 1.322±0.06 g/cm3(Predicted) |
| 熔点 | 119-1200C |
| 沸点 | 586.8±50.0 °C(Predicted) |
| 闪点 | 308.659°C |
| 蒸汽压 | 0mmHg at 25°C |
| 溶解度 | Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml). |
| 折射率 | 1.621 |
| 酸度系数 | 7.00±0.10(Predicted) |
| 存储条件 | room temp |
| 稳定性 | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
| 外观 | powder |
| 颜色 | white to beige |
| 产品用途 | An EGFR-tyrosine kinase inhibitor |