| 中文名 | 替米可新 |
| 英文名 | tilmicosin |
| 别名 | 替米可新 替米考星 替米考星碱 替米考星(替米卡星) 替米考星溶液, 100PPM 替米考星108050-54-0 替米考星 TILMICOSIN TILMICOSIN 替米考星 替米考星溶液, 1000PPM TILMICOSIN (标准品) 4A-O-脱(2,6-二去氧-3-C-甲基-L-核糖-吡喃己基)-20-脱氧-20-(3,5-二甲基-1-哌啶基)泰乐菌素 |
| 英文别名 | pulmotil tilmicosin Tilmicosine Tilmicosinbase Antibiotic EL 870 Tilmicosin (250 mg) Tilmicosin, Vetranal Herba Dianthi Superbi 20-DEOXO-20-(3,5-DIMETHYL-1-PIPERIDINYL)DESMYCOSIN 20-Deoxy-20-(3,5-diMethylpiperidin-1-yl)-desMycosin, EL-870 Tilmicosin,20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]- 4'-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)tyrosine [antibiotic] Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-.alpha.-L-ribo-hexopyranosyl)-20-deoxo-20-(3R,5S)-3,5-dimethyl-1-piperidinyl- (11Z,13Z)-6-{[4-(diMethylaMino)-3,5-dihydroxy-6-Methyloxan-2-yl]oxy}-7-[2-(3,5-diMethylpiperidin-1-yl)ethyl]-16-ethyl-4-hydroxy-15-{[(5-hydroxy-3,4-diMethoxy-6-Methyloxan-2-yl)oxy]Methyl}-5,9,13-triMethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-3-(dimethylamino)-beta-D-glucopyranosyl]oxy}-11-{2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]ethyl}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxooxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside |
| CAS | 108050-54-0 |
| EINECS | 639-676-2 |
| 化学式 | C46H80N2O13 |
| 分子量 | 869.15 |
| InChI | InChI=1/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1 |
| InChIKey | JTSDBFGMPLKDCD-XVFHVFLVSA-N |
| 密度 | 1.18±0.1 g/cm3(Predicted) |
| 熔点 | >97°C (dec.) |
| 沸点 | 926.6±65.0 °C(Predicted) |
| 比旋光度 | D23 +12.75° (c = 0.010004 in CHCl3, 5 cm) |
| 闪点 | 514.2°C |
| 蒸汽压 | 0mmHg at 25°C |
| 溶解度 | Acetone (Slightly), DMSO (Slightly), Methanol (Sparingly) |
| 折射率 | 1.545 |
| 酸度系数 | pKa (66% DMF): 7.4, 8.5(at 25℃) |
| 存储条件 | Inert atmosphere,Store in freezer, under -20°C |
| 外观 | neat |
| 颜色 | White to Off-White |
| 物化性质 | 白色或白色粉末湿度：≤5.0% |
| 产品用途 | 主要用于治疗胸膜肺炎、放线杆菌、巴氏杆菌及支原体引起的感染 |