| 中文名 | 替卡格雷 |
| 英文名 | (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol |
| 别名 | 替卡格雷 提卡格雷 替格瑞洛 替卡格雷标准品 替卡格雷及中间体 替卡格雷,替格瑞洛 替卡格雷,替格雷洛,替格瑞洛 (1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-二氟苯)环丙基]氨基}-5-(丙基硫氧嘧啶)-3H-[1,2,3]-三唑磷[4,5-D]嘧啶-3-基]-5-(2-羟乙基)环戊烷-1,2-二醇 |
| 英文别名 | Possia AZD6140 Brilinta Ticagrelo Ticagrelor AR-C126532 Ticargrelor AR-C 126532XX Ticagrelor Standards Ticagrelor and intermediates (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol 1,2-Cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)- |
| CAS | 274693-27-5 |
| EINECS | 619-540-9 |
| 化学式 | C23H28F2N6O4S |
| 分子量 | 522.57 |
| InChI | InChI=1/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15?,16?,17-,19-,20+/m0/s1 |
| 密度 | 1.67 |
| 熔点 | 138-140°C |
| 沸点 | 777.6±70.0 °C(Predicted) |
| 溶解度 | Methanol (Slightly) |
| 折射率 | 1.744 |
| 酸度系数 | 13.26±0.70(Predicted) |
| 存储条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| 稳定性 | Hygroscopic |
| 外观 | Solid |
| 颜色 | White to Off-White |
| 产品用途 | A reversible antagonist of the platelet purinergic P2Y12 receptor |